Serum biochemical parameters determination ALT and AST were estimated by IFCC method ALP by para- nitrophenyl phosphate method total cholesterol by enzymatic method triglycerides by glycerol phosphate oxidase method HDL-c by the ultra HDL assay, total bilirubin by diazonium saltmethod direct bilirubin by diazoreaction method plasma glucose by the oxidase-peroxidase method urea by Urease- GLDH method creatinine by kinetic alkaline picrate method uric acid by uricase-peroxidase method  were analyzed following to the reported methods.
At the end of the study end of the third weekthe rats were sacrificed by cervical dislocation.
Effect of treatment with Punica granatum peel methanolic extract on liver functions of rat model of liver fibrosis. In this feasibility study, the hepatoprotective effect of curcumin was investigated using a rat liver cirrhosis model, which was induced with dimethylnitrosamine DMN.
According to Rathod et al. Statistical Analysis The relative optical densities of various immunolabeled cells were measured and analyzed using ImageJ software Ver.
Trusolino L, Comoglio P M. Glycation inhibitory activity and the identification of an active compound in Plantago asiatica extract. Livers were excised for histology.
Blood sampling Twelve hours after the last intraperitoneal injection of CCl4, blood samples from these treated rats were drawn from their carotid arteries after being anesthetized under a light ethyl ether. This suggests that liver tissues can exhibit uniform distribution of electrical tissue conductivity.
Alanine amino transferase ALTaspartate amino transferase ASTalkaline phosphatase ALPtotal cholesterol, triglycerides, high density lipoprotein HDL-cbilirubin direct and total, glucose, total protein, urea, creatinine and acid uric kits were purchased from Biosystems, Spain.
Furthermore, the feeding of ODSO alone did not affect the growth performance in healthy rats. Weight of the animals was recorded weekly for 4 weeks. In the normal control group, PBS alone was injected in the same manner.
In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a totalpomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. The significance of the difference between the experimental and control groups in terms of liver tissue damage score was performed with the Kruskal—Wallis test.
Since it is involved in the biochemical conversions of various endogenous and exogenously administered substances, there is a possibility of generating various highly reactive species of free radicals, Kiuchi, To evaluate the potential efficacy of soapwort, pomegranate and cloves in protecting liver tissues from damage in CCl4-intoxicated mice.
J Pharm Pharm Sci;10 3: Fatty acid composition of the pomegranate seed oil used in the trial Click here to view Animals Experiments were performed using — g weighing, 80 adult male Wistar albino rats. Serum hepatocyte growth factor HGF was significantly increased in rats administered TAA as compared to the negative control ones.
Lipid peroxidation and irreversible damage in the rat hepatocyte model. Pomegranate juice consumption reduces oxidative stress, atherogenic modification to LDL, and platelet aggregation: Moreover, it has been found that the increase tissue MDA levels due to bile duct ligation BDL are also reduced back to control levels by treatment with pomegranate peel extract PPE in rats .
TAA is known to induce hepatocyte damage following its metabolism to thioacetamide sulphene and sulphone, via a critical pathway involving cytochrome Pmediated . NADPH, in turn, is generated via the hexose monophosphate shunt by a .
Gamma-mangostin, a novel type of 5-hydroxytryptamine 2A receptor antagonist.
Regarding the process by which CCL4 acts in the liver, the generation of free radicals has a crucial role in the hepatotoxic effect .The present study was Trichloroacetic acid (TCA) is a prominent by-product of the chlorination of drinking water. It induces cell damage by producing free radicals and reactive oxygen species.
Previous Reports have linked vitamin C with hepatoprotective property and its synergistic hepatoprotective effect with other antioxidants was also reported (Tawfik and Al Badr, ; Yu et al., ).
The present study was thus designed to evaluate the protective effect of vitamin C on the toxic effect of potassium bromate on the liver of.
Hepatoprotective effect was evaluated by comparing serum transaminase levels, bilirubin levels, albumin, and protein levels, coagulograms and pathohistological exams. We also measured flow rate by Doppler ultrasound of hepatic artery and portal vein before and after preconditioning.
Emblica officinalis – A histological study A I Mir 1, B Kumar, SA Tasduq, D K Gupta, S Bhardwaj* & R K Johri † Division of Pharmacology, Indian Institute of Integrative Medicine, (Formerly Regional Research Laboratory).
The present study was carried out to determine the phenolic and flavonoid contents of Derik pomegranate juice and determine its effect against carbon tetrachloride (CCl 4)-induced toxicity in rats.
The aim of this study was to determine whether antioxidant pomegranate seed extract (PSE) has a preventive effect on cisplatin-induced hepatotoxicity. Rabbits were divided into 3 groups (n=6)Download